Neurology

This is a new literature review updated in May 2022. In case some essential information is missing, please contact us at : rafael@hcuge.ch.

Post-COVID-19 persistent headache: A multicentric 9-months follow-up study of 905 patients

Garcia-Azorin D, Layos-Romero A, Porta-Etessam J, Membrilla JA, Caronna E, Gonzalez-Martinez A, Mencia ÁS, Segura T, Gonzalez-García N, Díaz-de-Terán J, Gallardo VJ, Gago-Veiga AB, Ballvé A, Trigo López J, Sastre-Real M, Llauradó A, Cornejo A, de Lorenzo Í, Guerrero-Peral Á, Pozo-Rosich P. Cephalalgia. 2022 Feb 15:3331024211068074. doi: 10.1177/03331024211068074. Epub ahead of print. PMID: 35166156.

This is a post-hoc multicenter ambisective study including patients from six different third-level hospitals in Spain between 1 March and 27 April 2020. Patients completed 9 months of neurological follow-up. We included 905 patients. Their median age was 51 (IQR 45-65), 66.5% were female, and 52.7% had a prior history of primary headache. The median duration of headache was 14 (6-39) days; however, the headache persisted after 3 months in 19.0% (95% CI: 16.5-21.8%) and after 9 months in 16.0% (95% confidence interval: 13.7-18.7%). Headache intensity during the acute phase was associated with a more prolonged duration of headache (Hazard ratio 0.655; 95% confidence interval: 0.582-0.737).The median duration of headache was 2 weeks, but in approximately a fifth of patients it became persistent and followed a chronic daily pattern.

Link to study : Post-COVID-19 persistent headache: A multicentric 9-months follow-up study of 905 patients

Visual interpretation of brain hypometabolism related to neurological long COVID: a French multicentric experience

Verger A, Kas A, Dudouet P, Goehringer F, Salmon-Ceron D, Guedj E.. Eur J Nucl Med Mol Imaging. 2022 Mar 23:1–6. doi: 10.1007/s00259-022-05753-5. Epub ahead of print. PMID: 35320385; PMCID: PMC8941296.

Link to study : Visual interpretation of brain hypometabolism related to neurological long COVID: a French multicentric experience

Changes in cognitive functioning after COVID-19: A systematic review and meta-analysis 

Crivelli L, Palmer K, Calandri I, Guekht A, Beghi E, Carroll W, Frontera J, García-Azorín D, Westenberg E, Winkler AS, Mangialasche F, Allegri RF, Kivipelto M. Alzheimers Dement. 2022 Mar 17. doi: 10.1002/alz.12644. Epub ahead of print. PMID: 35297561.

Link to study : Changes in cognitive functioning after COVID-19: A systematic review and meta-analysis