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Assessment of the Frequency and Variety of Persistent Symptoms Among Patients With COVID-19: A Systematic Review 

Nasserie T, Hittle M, Goodman SN. JAMA Netw Open. 2021 May 3;4(5):e2111417. doi: 10.1001/jamanetworkopen.2021.11417. PMID: 34037731; PMCID: PMC8155823.

A search of PubMed and Web of Science was conducted to identify studies (English language) published from January 1, 2020, to March 11, 2021, that examined persistent symptoms after COVID-19 infection. Persistent symptoms were defined as those persisting for at least 60 days after diagnosis, symptom onset, or hospitalization or at least 30 days after recovery from the acute illness or hospital discharge. 
A total of 1974 records were identified; of those, 1247 article titles and abstracts were screened, 47 studies were deemed eligible, and 45 studies reporting 84 clinical signs or symptoms were included. Of 9751 total participants, 5266 (54.0%) were male; 30 of 45 studies reported mean or median ages younger than 60 years. 
There were wide variations in the design and quality of the studies, which had implications for interpretation and often limited direct comparability and combinability. Individual symptoms occurring most frequently included shortness of breath or dyspnea (26 studies; median frequency, 36.0%; IQR, 27.6%-50.0%), fatigue or exhaustion (25 studies; median frequency, 40.0%; IQR, 31.0%-57.0%), and sleep disorders or insomnia (8 studies; median 29.4%, IQR, 24.4%-33.0%). 

Link to study : Assessment of the Frequency and Variety of Persistent Symptoms Among Patients With COVID-19: A Systematic Review

Post-acute COVID-19 syndrome 

Nalbandian A, Sehgal K, Gupta A, Madhavan MV, McGroder C, Stevens JS, Cook JR, Nordvig AS, Shalev D, Sehrawat TS, Ahluwalia N, Bikdeli B, Dietz D, Der-Nigoghossian C, Liyanage-Don N, Rosner GF, Bernstein EJ, Mohan S, Beckley AA, Seres DS, Choueiri TK, Uriel N, Ausiello JC, Accili D, Freedberg DE, Baldwin M, Schwartz A, Brodie D, Garcia CK, Elkind MSV, Connors JM, Bilezikian JP, Landry DW, Wan EY. Nat Med. 2021 Apr;27(4):601-615. doi: 10.1038/s41591-021-01283-z. Epub 2021 Mar 22. PMID: 33753937.

A review of the literature on post-COVID condition, with timeline of infection, an overview of sequelae, potential pathophysiology and an interdisciplinary approach for management considerations. 

Link to study : Post-acute COVID-19 syndrome